李政怡老師實驗室

 

                                                                                                                 

生物化學暨生物物理實驗室

Biochemistry and Biophysics Lab.

                                                                              

李政怡教授

 

Dr. Cheng-I (Sophia) Lee

Professor

Department of Biomedical Sciences

Email: biocil@ccu.edu.tw

Tel: 886-5-2720411 #66511 (office) #61523 (lab),

886-5-2729157 (direct call)

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Education and Experiences

B. S., Chemistry, National Tsing Hua University, Taiwan                            

M. S., Chemistry, National Tsing Hua University, Taiwan                           

Ph. D., Chemistry, Yale University, USA                            

Post-Doctoral Associate, Medical Biotechnology Center, University of Maryland Biotechnology Institute, USA                                                                

Assistant Professor, Life Science, National Chung Cheng University, Taiwan  

Associate Professor, Life Science, National Chung Cheng University, Taiwan   

Associate Professor, Biomedical Sciences, National Chung Cheng University, Taiwan  

Professor, Biomedical Sciences, National Chung Cheng University, Taiwan

Biography

Dr. Cheng-I Lee has completed her PhD from Yale University in USA and her postdoctoral study from Biomedical Research Center in University of Maryland in USA. She has strong interest in interdisciplinary studies. She started her independent research in National Chung Cheng University in 2007. She works on misfolding of amyloid proteins, such as prion, beta amyloid and gama D crystallin. Recently, she starts working on phytochemical treatmenst and photo-induced therapies on tumors and Candida species. Nanotechnology has been applied in the studies of photo-induced therapies.

Research interests

  • Targeting therapy
  • Photo-induced therapy
  • Nanomedicine
  • Protein misfolding
  • Application of phytochemicals

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研究內容

  • 標靶治療開發
  • 光動力療法
  • 奈米醫藥
  • 蛋白質錯誤摺疊與纖維化
  • 植化素之應用

 

Selected publication

  1. Wen-Hsuan Tsai, Kun-Hua Yu, Yi-Cheng Huang and Cheng-I Lee*, “EGFR-targeted photodynamic therapy by curcumin-encapsulated chitosan/TPP nanoparticles” International Journal of Nanomedicine (2018) 13, 903-916 (doi: 10.2147/Ijn.S148305).
  2. Yi-Hsuan Hsieh, Wen-Ching Chuang, Kun-Hua Yu, Cheng-Ping Jheng and Cheng-I Lee*, “Sequential Photodynamic Therapy with Phthalocyanine Encapsulated Chitosan-Tripolyphosphate Nanoparticles and Flucytosine Treatment against Candida tropicalisPharmaceutics (2019) 11, 16 (doi: 10.3390/pharmaceutics11010016).
  3. Yi-Hsuan Hsieh, Jun-Hui Zhang, Wen-Ching Chuang, Kun-Hua Yu, Xian-Bin Huang, Yao-Chang Lee and Cheng-I Lee*, “An in Vitro Study on Effect of Combined Treatment with Photodynamic and Chemical Therapies on Candida albicansInternational Journal of Molecular Science (2018) 19, 337 (doi: 10.3390/ijms19020337).

實驗室成員Members